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Chance, destiny, and the inner workings of ClpXP

AAA+ proteases are responsible for protein degradation in all branches of life. Using single molecule and ensemble assays, Cordova et al. (2014) investigate how the bacterial protease ClpXP steps through a substrate’s polypeptide chain and construct a quantitative kinetic model that recapitulates th...

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Foilsithe in:Cell
Main Authors: Russell, Rick, Matouschek, Andreas
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945115/
https://ncbi.nlm.nih.gov/pubmed/25083864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.009
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