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Chance, destiny, and the inner workings of ClpXP
AAA+ proteases are responsible for protein degradation in all branches of life. Using single molecule and ensemble assays, Cordova et al. (2014) investigate how the bacterial protease ClpXP steps through a substrate’s polypeptide chain and construct a quantitative kinetic model that recapitulates th...
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| Pubblicato in: | Cell |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945115/ https://ncbi.nlm.nih.gov/pubmed/25083864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.009 |
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