Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP

ClpX and ClpA are molecular chaperones that interact with specific proteins and, together with ClpP, activate their ATP-dependent degradation. The chaperone activity is thought to convert proteins into an extended conformation that can access the sequestered active sites of ClpP. We now show that Cl...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Singh, Satyendra K., Grimaud, Regis, Hoskins, Joel R., Wickner, Sue, Maurizi, Michael R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10922052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.16.8898
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