ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP
AAA+ proteases perform regulated protein degradation in all kingdoms of life and consist of a hexameric AAA+ unfoldase/translocase in complex with a self-compartmentalized peptidase. Based on asymmetric features of cryo-EM structures and a sequential hand-over-hand model of substrate translocation,...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications Ltd
2020-12-01
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| Colección: | eLife |
| Materias: | |
| Acceso en línea: | https://elifesciences.org/articles/61451 |
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