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Translocation pathway of protein substrates in ClpAP protease

Intracellular protein degradation, which must be tightly controlled to protect normal proteins, is carried out by ATP-dependent proteases. These multicomponent enzymes have chaperone-like ATPases that recognize and unfold protein substrates and deliver them to the proteinase components for digestion...

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Autori principali: Ishikawa, Takashi, Beuron, Fabienne, Kessel, Martin, Wickner, Sue, Maurizi, Michael R., Steven, Alasdair C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC31834/
https://ncbi.nlm.nih.gov/pubmed/11287666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081543698
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