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ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence

Clp/Hsp100 ATPases comprise a large family of ATP-dependent chaperones, some of which are regulatory components of two-component proteases. Substrate specificity resides in the Clp protein and the current thinking is that Clp proteins recognize motifs located near one or the other end of the substra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoskins, Joel R., Yanagihara, Katsuhiko, Mizuuchi, Kiyoshi, Wickner, Sue
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123206/
https://ncbi.nlm.nih.gov/pubmed/12177439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172378899
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