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ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence

Clp/Hsp100 ATPases comprise a large family of ATP-dependent chaperones, some of which are regulatory components of two-component proteases. Substrate specificity resides in the Clp protein and the current thinking is that Clp proteins recognize motifs located near one or the other end of the substra...

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Detalhes bibliográficos
Main Authors: Hoskins, Joel R., Yanagihara, Katsuhiko, Mizuuchi, Kiyoshi, Wickner, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123206/
https://ncbi.nlm.nih.gov/pubmed/12177439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172378899
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