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The Role of Cholesterol in Driving IAPP-Membrane Interactions
Our knowledge of the molecular events underlying type 2 diabetes mellitus—a protein conformational disease characterized by the aggregation of islet amyloid polypeptide (IAPP) in pancreatic β cells—is limited. However, amyloid-mediated membrane damage is known to play a key role in IAPP cytotoxicity...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4944530/ https://ncbi.nlm.nih.gov/pubmed/27410742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.050 |
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