Cations as Switches of Amyloid-Mediated Membrane Disruption Mechanisms: Calcium and IAPP

Disruption of the integrity of the plasma membrane by amyloidogenic proteins is linked to the pathogenesis of a number of common age-related diseases. Although accumulating evidence suggests that adverse environmental stressors such as unbalanced levels of metal ions may trigger amyloid-mediated mem...

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Detalhes bibliográficos
Main Authors: Sciacca, Michele F.M., Milardi, Danilo, Messina, Grazia M.L., Marletta, Giovanni, Brender, Jeffrey R., Ramamoorthy, Ayyalusamy, La Rosa, Carmelo
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540246/
https://ncbi.nlm.nih.gov/pubmed/23332070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.11.3811
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