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Phosphatidylethanolamine enhances amyloid fiber dependent membrane fragmentation

The toxicity of amyloid-forming peptides has been hypothesized to reside in the ability of protein oligomers to interact with and disrupt the cell membrane. Much of the evidence for this hypothesis comes from in vitro experiments using model membranes. However, the accuracy of this approach depends...

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Библиографические подробности
Главные авторы: Sciacca, Michele F.M., Brender, Jeffrey R., Lee, Dong-Kuk, Ramamoorthy, Ayyalusamy
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464957/
https://ncbi.nlm.nih.gov/pubmed/22970795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3009888
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