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Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation
Disruption of cell membranes by Aβ is believed to be one of the key components of Aβ toxicity. However, the mechanism by which this occurs is not fully understood. Here, we demonstrate that membrane disruption by Aβ occurs by a two-step process, with the initial formation of ion-selective pores foll...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443794/ https://ncbi.nlm.nih.gov/pubmed/22947931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.045 |
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