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Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes?

The activity of antimicrobial peptides has been shown to depend on the composition of the target cell membrane. The bacterial selectivity of most antimicrobial peptides has been attributed to the presence of abundant acidic phospholipids and the absence of cholesterol in bacterial membranes. The hig...

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Detalhes bibliográficos
Main Authors: McHenry, Austin J., Sciacca, Michele F. M., Brender, Jeffrey R., Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455134/
https://ncbi.nlm.nih.gov/pubmed/22885355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.07.021
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