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Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular prospective

The aggregation of proteins is tightly controlled in living systems, and misfolded proteins are normally removed before aggregation of the misfolded protein can occur. But for reasons not clearly understood, in some individuals this degradation process breaks down, and misfolded proteins accumulate...

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Main Authors: Brender, Jeffrey R., Salamekh, Samer, Ramamoorthy, Ayyalusamy
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272313/
https://ncbi.nlm.nih.gov/pubmed/21942864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar200189b
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