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Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular prospective

The aggregation of proteins is tightly controlled in living systems, and misfolded proteins are normally removed before aggregation of the misfolded protein can occur. But for reasons not clearly understood, in some individuals this degradation process breaks down, and misfolded proteins accumulate...

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Detalhes bibliográficos
Main Authors: Brender, Jeffrey R., Salamekh, Samer, Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272313/
https://ncbi.nlm.nih.gov/pubmed/21942864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar200189b
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