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Antimicrobial and Membrane Disrupting Activities of a Peptide Derived from the Human Cathelicidin Antimicrobial Peptide LL37

A 21-residue peptide segment, LL7-27 (RKSKEKIGKEFKRIVQRIKDF), corresponding to residues 7–27 of the only human cathelicidin antimicrobial peptide, LL37, is shown to exhibit potent activity against microbes (particularly Gram-positive bacteria) but not against erythrocytes. The structure, membrane or...

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Detalhes bibliográficos
Main Authors: Thennarasu, Sathiah, Tan, Anmin, Penumatchu, Rajesh, Shelburne, Charles E., Heyl, Deborah L., Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808482/
https://ncbi.nlm.nih.gov/pubmed/20338846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.060
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