Deletion of All Cysteines in Tachyplesin I Abolishes Hemolytic Activity and Retains Antimicrobial Activity and LPS Selective Binding

Tachyplesin-I is a cyclic β-sheet antimicrobial peptide isolated from the hemocytes of Tachypleus tridentatus. The four cysteine residues in Tachyplesin I play a structural role in imparting amphipathicity to the peptide which has been shown to be essential for its activity. We investigated the role...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ramamoorthy, Ayyalusamy, Thennarasu, Sathiah, Tan, Anmin, Gottipati, Kiran, Sreekumar, Sreeja, Heyl, Deborah L., An, Florence Y.P., Shelburne, Charles E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515376/
https://ncbi.nlm.nih.gov/pubmed/16700563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052629q
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky