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Solid-State NMR Investigation of the Membrane-Disrupting Mechanism of Antimicrobial Peptides MSI-78 and MSI-594 Derived from Magainin 2 and Melittin

The mechanism of membrane interaction of two amphipathic antimicrobial peptides, MSI-78 and MSI-594, derived from magainin-2 and melittin, is presented. Both the peptides show excellent antimicrobial activity. The 8-anilinonaphthalene-1-sulfonic acid uptake experiment using Escherichia coli cells su...

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Detalhes bibliográficos
Main Authors: Ramamoorthy, Ayyalusamy, Thennarasu, Sathiah, Lee, Dong-Kuk, Tan, Anmin, Maloy, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479060/
https://ncbi.nlm.nih.gov/pubmed/16603496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073890
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