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Membrane Thinning Due to Antimicrobial Peptide Binding: An Atomic Force Microscopy Study of MSI-78 in Lipid Bilayers

The interaction of an antimicrobial peptide, MSI-78, with phospholipid bilayers has been investigated using atomic force microscopy, circular dichroism, and nuclear magnetic resonance (NMR). Binding of amphipathic peptide helices with their helical axis parallel to the membrane surface leads to memb...

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Bibliografiske detaljer
Main Authors: Mecke, Almut, Lee, Dong-Kuk, Ramamoorthy, Ayyalusamy, Orr, Bradford G., Banaszak Holl, Mark M.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366969/
https://ncbi.nlm.nih.gov/pubmed/16183881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062596
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