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Membrane Thinning Due to Antimicrobial Peptide Binding: An Atomic Force Microscopy Study of MSI-78 in Lipid Bilayers

The interaction of an antimicrobial peptide, MSI-78, with phospholipid bilayers has been investigated using atomic force microscopy, circular dichroism, and nuclear magnetic resonance (NMR). Binding of amphipathic peptide helices with their helical axis parallel to the membrane surface leads to memb...

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Détails bibliographiques
Auteurs principaux: Mecke, Almut, Lee, Dong-Kuk, Ramamoorthy, Ayyalusamy, Orr, Bradford G., Banaszak Holl, Mark M.
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366969/
https://ncbi.nlm.nih.gov/pubmed/16183881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062596
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