Loading...

Synthetic and Natural Polycationic Polymer Nanoparticles Interact Selectively with Fluid-Phase Domains of DMPC Lipid Bilayers

Polycationic polymers are known to disrupt lipid bilayers. In this letter, we report the dependence of this disruption on the lipid structural phase. DMPC bilayers are exposed to two polycationic polymeric nanoparticles, PAMAM dendrimers and MSI-78. We find that regions of the bilayer that are in th...

Full description

Saved in:
Bibliographic Details
Main Authors: Mecke, Almut, Lee, Dong-Kuk, Ramamoorthy, Ayyalusamy, Orr, Bradford G., Banaszak Holl, Mark M.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440293/
https://ncbi.nlm.nih.gov/pubmed/16142931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la051800w
Tags: Add Tag
No Tags, Be the first to tag this record!