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Bioinspired, size-tunable self-assembly of polymer-lipid bilayer nanodiscs

Polymer-based nanodiscs are valuable tools in biomedical research that can offer a detergent-free solubilization of membrane proteins maintaining their native lipid environment. Here, we introduce a novel ~1.6 kDa SMA-based polymer with styrene:maleic acid moieties that can form nanodiscs containing...

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書目詳細資料
發表在:Angew Chem Int Ed Engl
Main Authors: Ravula, Thirupathi, Ramadugu, Sudheer Kumar, Di Mauro, Giacomo, Ramamoorthy, Ayyalusamy
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600881/
https://ncbi.nlm.nih.gov/pubmed/28714233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201705569
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