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MSI-78, an Analogue of the Magainin Antimicrobial Peptides, Disrupts Lipid Bilayer Structure via Positive Curvature Strain

In this work, we present the first characterization of the cell lysing mechanism of MSI-78, an antimicrobial peptide. MSI-78 is an amphipathic α-helical peptide designed by Genaera Corporation as a synthetic analog to peptides from the magainin family. (31)P-NMR of mechanically aligned samples and d...

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Hlavní autoři: Hallock, Kevin J., Lee, Dong-Kuk, Ramamoorthy, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302867/
https://ncbi.nlm.nih.gov/pubmed/12719236
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