Загрузка...
Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity
Human APOBEC3B (A3B) is a member of the APOBEC3 (A3) family of cytidine deaminases, which function as DNA mutators and restrict viral pathogens and endogenous retrotransposons. Recently, A3B was identified as a major source of genetic heterogeneity in several human cancers. Here, we determined the s...
Сохранить в:
| Опубликовано в: : | Biochemistry |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4943463/ https://ncbi.nlm.nih.gov/pubmed/27163633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00382 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|