A carregar...

Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity

Human APOBEC3B (A3B) is a member of the APOBEC3 (A3) family of cytidine deaminases, which function as DNA mutators and restrict viral pathogens and endogenous retrotransposons. Recently, A3B was identified as a major source of genetic heterogeneity in several human cancers. Here, we determined the s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Byeon, In-Ja L., Byeon, Chang-Hyeock, Wu, Tiyun, Mitra, Mithun, Singer, Dustin, Levin, Judith G., Gronenborn, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943463/
https://ncbi.nlm.nih.gov/pubmed/27163633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00382
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!