PIAS1 regulates mutant Huntingtin accumulation and Huntington’s disease-associated phenotypes in vivo

The disruption of protein quality control networks is central to pathology in Huntington’s disease (HD) and other neurodegenerative disorders. The aberrant accumulation of insoluble high molecular weight protein complexes containing the Huntingtin (HTT) protein and SUMOylated protein corresponds to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Ochaba, Joseph, Monteys, Alex Mas, O’Rourke, Jacqueline G., Reidling, Jack C., Steffan, Joan S., Davidson, Beverly L., Thompson, Leslie M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942306/
https://ncbi.nlm.nih.gov/pubmed/27146268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.03.016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker