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MutSα maintains the mismatch repair capability by inhibiting PCNA unloading
Eukaryotic mismatch repair (MMR) utilizes single-strand breaks as signals to target the strand to be repaired. DNA-bound PCNA is also presumed to direct MMR. The MMR capability must be limited to a post-replicative temporal window during which the signals are available. However, both identity of the...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942255/ https://ncbi.nlm.nih.gov/pubmed/27402201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15155 |
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