Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components

The CMG complex composed of Mcm2-7, Cdc45 and GINS is postulated to be the eukaryotic replicative DNA helicase, whose activation requires sequential recruitment of replication proteins onto Mcm2-7. Current models suggest that Mcm10 is involved in assembly of the CMG complex, and in tethering of DNA...

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Detaylı Bibliyografya
Asıl Yazarlar: Kanke, Mai, Kodama, Yukako, Takahashi, Tatsuro S, Nakagawa, Takuro, Masukata, Hisao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343466/
https://ncbi.nlm.nih.gov/pubmed/22433840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.68
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