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Multiple ORC-binding sites are required for efficient MCM loading and origin firing in fission yeast

In most eukaryotes, replication origins are composed of long chromosome regions, and the exact sequences required for origin recognition complex (ORC) and minichromosome maintenance (MCM) complex association remain elusive. Here, we show that two stretches of adenine/thymine residues are collectivel...

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Main Authors: Takahashi, Tatsuro, Ohara, Eri, Nishitani, Hideo, Masukata, Hisao
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC145439/
https://ncbi.nlm.nih.gov/pubmed/12574132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg079
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