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Multiple ORC-binding sites are required for efficient MCM loading and origin firing in fission yeast

In most eukaryotes, replication origins are composed of long chromosome regions, and the exact sequences required for origin recognition complex (ORC) and minichromosome maintenance (MCM) complex association remain elusive. Here, we show that two stretches of adenine/thymine residues are collectivel...

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Bibliografiske detaljer
Main Authors: Takahashi, Tatsuro, Ohara, Eri, Nishitani, Hideo, Masukata, Hisao
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC145439/
https://ncbi.nlm.nih.gov/pubmed/12574132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg079
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