Multiple ORC-binding sites are required for efficient MCM loading and origin firing in fission yeast

In most eukaryotes, replication origins are composed of long chromosome regions, and the exact sequences required for origin recognition complex (ORC) and minichromosome maintenance (MCM) complex association remain elusive. Here, we show that two stretches of adenine/thymine residues are collectivel...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Takahashi, Tatsuro, Ohara, Eri, Nishitani, Hideo, Masukata, Hisao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574132/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg079
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