Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation

Fission yeast centromeres are transcriptionally silent and form a heterochromatin-like structure essential for normal centromere function; this appears analogous to heterochromatin and position effect variegation in other eukaryotes. Conditional mutations in three genes designated cep (centromere en...

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Bibliographic Details
Main Authors: Javerzat, Jean-Paul, McGurk, Gordon, Cranston, Gwen, Barreau, Christian, Bernard, Pascal, Gordon, Colin, Allshire, Robin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84358/
https://ncbi.nlm.nih.gov/pubmed/10373564
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