Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation

Fission yeast centromeres are transcriptionally silent and form a heterochromatin-like structure essential for normal centromere function; this appears analogous to heterochromatin and position effect variegation in other eukaryotes. Conditional mutations in three genes designated cep (centromere en...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Javerzat, Jean-Paul, McGurk, Gordon, Cranston, Gwen, Barreau, Christian, Bernard, Pascal, Gordon, Colin, Allshire, Robin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373564/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.5155
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