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DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast

DNA polymerase epsilon (Pol ε) synthesizes the leading strands, following the CMG (Cdc45, Mcm2-7, and GINS [Go-Ichi-Nii-San]) helicase that translocates on the leading-strand template at eukaryotic replication forks. Although Pol ε is essential for the viability of fission and budding yeasts, the N-...

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Autors principals: Handa, Tetsuya, Kanke, Mai, Takahashi, Tatsuro S., Nakagawa, Takuro, Masukata, Hisao
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418317/
https://ncbi.nlm.nih.gov/pubmed/22718908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0339
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