Disorder transitions and conformational diversity cooperatively modulate biological function in proteins

Structural differences between conformers sustain protein biological function. Here, we studied in a large dataset of 745 intrinsically disordered proteins, how ordered‐disordered transitions modulate structural differences between conformers as derived from crystallographic data. We found that almo...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Zea, Diego Javier, Monzon, Alexander Miguel, Gonzalez, Claudia, Fornasari, María Silvina, Tosatto, Silvio C. E., Parisi, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941770/
https://ncbi.nlm.nih.gov/pubmed/27038125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2931
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