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Addressing the Role of Conformational Diversity in Protein Structure Prediction

Computational modeling of tertiary structures has become of standard use to study proteins that lack experimental characterization. Unfortunately, 3D structure prediction methods and model quality assessment programs often overlook that an ensemble of conformers in equilibrium populates the native s...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Palopoli, Nicolas, Monzon, Alexander Miguel, Parisi, Gustavo, Fornasari, Maria Silvina
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861349/
https://ncbi.nlm.nih.gov/pubmed/27159429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154923
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