Conformational diversity analysis reveals three functional mechanisms in proteins

Protein motions are a key feature to understand biological function. Recently, a large-scale analysis of protein conformational diversity showed a positively skewed distribution with a peak at 0.5 Å C-alpha root-mean-square-deviation (RMSD). To understand this distribution in terms of structure-func...

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Udgivet i:PLoS Comput Biol
Main Authors: Monzon, Alexander Miguel, Zea, Diego Javier, Fornasari, María Silvina, Saldaño, Tadeo E., Fernandez-Alberti, Sebastian, Tosatto, Silvio C. E., Parisi, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330503/
https://ncbi.nlm.nih.gov/pubmed/28192432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005398
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