Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

Chronic periodontitis (CP) is a chronic inflammatory disease independently associated with higher incidence of oral cavity squamous cell carcinoma (OSCC). However, the molecular mechanism responsible for this increased incidence is unknown. Here we profiled the DNA methylome of CP patients and healt...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Planello, Aline C., Singhania, Rajat, Kron, Ken J., Bailey, Swneke D., Roulois, David, Lupien, Mathieu, Line, Sérgio R. Peres, de Souza, Ana Paula, De Carvalho, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941276/
https://ncbi.nlm.nih.gov/pubmed/26908456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7513
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