Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

Chronic periodontitis (CP) is a chronic inflammatory disease independently associated with higher incidence of oral cavity squamous cell carcinoma (OSCC). However, the molecular mechanism responsible for this increased incidence is unknown. Here we profiled the DNA methylome of CP patients and healt...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Planello, Aline C., Singhania, Rajat, Kron, Ken J., Bailey, Swneke D., Roulois, David, Lupien, Mathieu, Line, Sérgio R. Peres, de Souza, Ana Paula, De Carvalho, Daniel D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941276/
https://ncbi.nlm.nih.gov/pubmed/26908456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7513
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