Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus

Genome-wide association studies (GWAS) are identifying genetic predisposition to various diseases. The 17q24.3 locus harbors the single nucleotide polymorphism (SNP) rs1859962 that is statistically associated with prostate cancer (PCa). It defines a 130-kb linkage disequilibrium (LD) block that lies...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaoyang, Cowper-Sal·lari, Richard, Bailey, Swneke D., Moore, Jason H., Lupien, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409257/
https://ncbi.nlm.nih.gov/pubmed/22665440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.135665.111
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