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ABC: a tool to identify SNVs causing allele-specific transcription factor binding from ChIP-Seq experiments

Motivation: Detection of allelic imbalances in ChIP-Seq reads is a powerful approach to identify functional non-coding single nucleotide variants (SNVs), either polymorphisms or mutations, which modulate the affinity of transcription factors for chromatin. We present ABC, a computational tool that i...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Bailey, Swneke D., Virtanen, Carl, Haibe-Kains, Benjamin, Lupien, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668780/
https://ncbi.nlm.nih.gov/pubmed/25995231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv321
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