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ABC: a tool to identify SNVs causing allele-specific transcription factor binding from ChIP-Seq experiments
Motivation: Detection of allelic imbalances in ChIP-Seq reads is a powerful approach to identify functional non-coding single nucleotide variants (SNVs), either polymorphisms or mutations, which modulate the affinity of transcription factors for chromatin. We present ABC, a computational tool that i...
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| 發表在: | Bioinformatics |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4668780/ https://ncbi.nlm.nih.gov/pubmed/25995231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv321 |
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