A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models

Single-chain variable fragments (scFvs) expressed as “intracellular antibodies” (intrabodies) can target intracellular antigens to hamper their function efficaciously and specifically. Here we use an intrabody targeting the E6 oncoprotein of Human papillomavirus 16 (HPV16) to address the issue of a...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Amici, Carla, Visintin, Michela, Verachi, Francesca, Paolini, Francesca, Percario, Zulema, Di Bonito, Paola, Mandarino, Angela, Affabris, Elisabetta, Venuti, Aldo, Accardi, Luisa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941259/
https://ncbi.nlm.nih.gov/pubmed/26788990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6925
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