A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models

Single-chain variable fragments (scFvs) expressed as “intracellular antibodies” (intrabodies) can target intracellular antigens to hamper their function efficaciously and specifically. Here we use an intrabody targeting the E6 oncoprotein of Human papillomavirus 16 (HPV16) to address the issue of a...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Amici, Carla, Visintin, Michela, Verachi, Francesca, Paolini, Francesca, Percario, Zulema, Di Bonito, Paola, Mandarino, Angela, Affabris, Elisabetta, Venuti, Aldo, Accardi, Luisa
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941259/
https://ncbi.nlm.nih.gov/pubmed/26788990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6925
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