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Sex differences in effects of ketamine on behavior, spine density and synaptic proteins in socially isolated rats

BACKGROUND: The mechanistic underpinnings of sex differences in occurrence of depression and efficacy of antidepressant treatments are poorly understood. Here we examined the effects of isolation stress and the fast acting antidepressant ketamine, on anhedonia and depression-like behavior, spine den...

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Dettagli Bibliografici
Pubblicato in:Biol Psychiatry
Autori principali: Sarkar, Ambalika, Kabbaj, Mohamed
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940294/
https://ncbi.nlm.nih.gov/pubmed/26957131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.12.025
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