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Sex differences in effects of ketamine on behavior, spine density and synaptic proteins in socially isolated rats

BACKGROUND: The mechanistic underpinnings of sex differences in occurrence of depression and efficacy of antidepressant treatments are poorly understood. Here we examined the effects of isolation stress and the fast acting antidepressant ketamine, on anhedonia and depression-like behavior, spine den...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Psychiatry
Hauptverfasser: Sarkar, Ambalika, Kabbaj, Mohamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940294/
https://ncbi.nlm.nih.gov/pubmed/26957131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.12.025
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