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Sex differences in effects of ketamine on behavior, spine density and synaptic proteins in socially isolated rats

BACKGROUND: The mechanistic underpinnings of sex differences in occurrence of depression and efficacy of antidepressant treatments are poorly understood. Here we examined the effects of isolation stress and the fast acting antidepressant ketamine, on anhedonia and depression-like behavior, spine den...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Sarkar, Ambalika, Kabbaj, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940294/
https://ncbi.nlm.nih.gov/pubmed/26957131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.12.025
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