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Sex Differences in the Pharmacokinetics of Low-dose Ketamine in Plasma and Brain of Male and Female Rats

Recent work from our group and others has revealed a higher sensitivity of female rodents to the antidepressant-like effects of the N-methyl d-aspartate receptor antagonist ketamine strongly influenced by circulating estrogen and progesterone levels. However, in the absence of any preclinical studie...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Saland, Samantha K., Kabbaj, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226548/
https://ncbi.nlm.nih.gov/pubmed/30213876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.251652
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