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Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density

Clinical and preclinical studies have shown that ketamine, an NMDA receptor antagonist, has promising therapeutic value for the treatment of alcohol use disorder (AUD). However, the maintenance of remission will ultimately require repeated infusions of ketamine, which may lead to abuse potential and...

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Publicat a:eNeuro
Autors principals: Strong, Caroline E., Wright, Katherine N., Kabbaj, Mohamed
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893233/
https://ncbi.nlm.nih.gov/pubmed/31740575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0221-19.2019
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