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Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density

Clinical and preclinical studies have shown that ketamine, an NMDA receptor antagonist, has promising therapeutic value for the treatment of alcohol use disorder (AUD). However, the maintenance of remission will ultimately require repeated infusions of ketamine, which may lead to abuse potential and...

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Publicado en:eNeuro
Main Authors: Strong, Caroline E., Wright, Katherine N., Kabbaj, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893233/
https://ncbi.nlm.nih.gov/pubmed/31740575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0221-19.2019
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