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Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density

Clinical and preclinical studies have shown that ketamine, an NMDA receptor antagonist, has promising therapeutic value for the treatment of alcohol use disorder (AUD). However, the maintenance of remission will ultimately require repeated infusions of ketamine, which may lead to abuse potential and...

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Détails bibliographiques
Publié dans:eNeuro
Auteurs principaux: Strong, Caroline E., Wright, Katherine N., Kabbaj, Mohamed
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893233/
https://ncbi.nlm.nih.gov/pubmed/31740575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0221-19.2019
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