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Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification
Human male germ cell tumors (GCTs) are derived from primordial germ cells (PGCs). The master pluripotency regulator and neuroectodermal lineage effector transcription factor SOX2 is repressed in PGCs and the seminoma (SEM) subset of GCTs. The mechanism of SOX2 repression and its significance to GC a...
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| Pubblicato in: | Stem Cell Reports |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939754/ https://ncbi.nlm.nih.gov/pubmed/27132888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.04.002 |
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