Cross-Platform Assessment of Genomic Imbalance Confirms the Clinical Relevance of Genomic Complexity and Reveals Loci with Potential Pathogenic Roles in Diffuse Large B-Cell Lymphoma

Genomic copy number alterations (CNAs) in diffuse large B-cell lymphoma (DLBCL) have roles in disease pathogenesis but overall clinical relevance remains unclear. Herein, an unbiased algorithm was uniformly applied across three genome profiling datasets comprising 392 newly-diagnosed DLBCL specimens...

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Détails bibliographiques
Publié dans:Leuk Lymphoma
Auteurs principaux: Dias, Lizalynn M., Thodima, Venkata, Friedman, Julia, Ma, Charles, Guttapalli, Asha, Mendiratta, Geetu, Siddiqi, Imran N., Syrbu, Sergei, Chaganti, R. S. K., Houldsworth, Jane
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963821/
https://ncbi.nlm.nih.gov/pubmed/26294112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2015.1080364
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