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Interrogation of a Context-Specific Transcription Factor Network Identifies Novel Regulators of Pluripotency

The predominant view of pluripotency regulation proposes a stable ground state with coordinated expression of key transcription factors (TFs) that prohibit differentiation. Another perspective suggests a more complexly regulated state involving competition between multiple lineage-specifying TFs tha...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kushwaha, Ritu, Jagadish, Nirmala, Kustagi, Manjunath, Tomishima, Mark J., Mendiratta, Geetu, Bansal, Mukesh, Kim, Hyunjae R., Sumazin, Pavel, Alvarez, Mariano J., Lefebvre, Celine, Villagrasa-Gonzalez, Patricia, Viale, Agnes, Korkola, James E., Houldsworth, Jane, Feldman, Darren R., Bosl, George J., Califano, Andrea, Chaganti, R. S. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305010/
https://ncbi.nlm.nih.gov/pubmed/25336442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1870
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